What parts of our body are affected by nicotine?

As nicotine enters the body, it is distributed quickly through the bloodstream and can cross the blood-brain barrier. On average it takes about 7 seconds for the substance to reach the brain when inhaled. The half life of nicotine in the body is around 2 hours.The amount of nicotine inhaled with tobacco smoke is a fraction of the amount contained in the tobacco leaves. Nicotine is metabolized in the liver by cytochrome P450 enzymes (mostly CYP2A6, and also by CYP2B6).

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Keywords: Nicotine Effect Metabolites

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