What is Neural Tube Defect?

Development of brain in embryo starts at during the 4th to 6th week after conception. It starts with the formation of the neural tube that later becomes the spinal cord, spine, brain, and the skull of the developing baby. A neural tube defect (NTD) occurs when the development of the neural tube is interrupted due to many factors that may vary from nutrient deficiency to accidental early death of the baby after delivery or may even result in the delivery of a dead baby. One of the main reasons of NTD is the deficiency of folic acid during pregnancy. Two most common neural tube defects are spina bifida and anencephaly encephalocele. In most cases, NTDs (up to 70%) can be prevented by including enough quantity of the B vitamin folic acid in every day diet before a woman gets pregnant.

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Keywords: Folic acid deficiency Spinal cord spine brain skull miscarriages

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