What is CRP?

CRP stands for C-reactive proteins that are the major acute proteins produced by liver in response to tissue damage. Their name derives from their pattern recognition activity as they act as soluble receptors which can recognize receptor patterns on microbial surface and bind to these surfaces and promote their opsonization. Precisely, C-reactive proteins bind to the C-polysaccharide cell-wall components found on a variety of bacteria & fungi. This binding activates the complement system, resulting in increase in pathogen lysis or phagocytosis. The release of C-reactive proteins is a part of the complex cascade of events involving a variety of chemical mediators required to initiate the inflammatory response. So, high levels of CRP in the blood indicate inflammation somewhere in the body. CRP levels not only increase in response to the foreign particle's invasion but may also increase/dicrease due to several other factors like age, genetic makeup, mutations etc.

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