What is cotinine?Cotinine is created in the body of habitual smokers when nicotine is metabolized, and builds up gradually over time if smoking is done regularly. Cotinine does not break down in body fluids and has a half-life of around 17 hours, making it easier to detect than nicotine or other nicotine metabolites since it is present in the body for a longer period of time. It is known as a common indicator of exposure to tobacco. Cotinine is tested for by various methods including gas chromatography, mass spectrometry, HPLC ( High Performance Liquid Chromatography) and other processes that generally require specialized equipment.
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