Adulteration is the tampering of a urine specimen with
the intention of altering the test results. The use of
adulterants can cause false negative results in drug
tests by either interfering with the screening test and/or
destroying the drugs present in the urine. Dilution may
also be employed in an attempt to produce false
negative drug test results.
One of the best ways to test for adulteration or dilution
is to determine certain urinary characteristics such as
creatinine, pH, and specific gravity and to detect the
presence of glutaraldehyde, nitrite and oxidants
/pyridinium chlorochromate (PCC) in urine.
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