What are the pharmacological uses of Nicotinic acid?
Nicotinic acid, when taken in large doses, blocks the breakdown of fats in adipose tissue, thus altering blood lipid levels. It is used in the treatment of hyperlipidemia because it reduces very-low-density lipoprotein (VLDL), a precursor of low-density lipoprotein (LDL) or bad cholesterol. Because nicotinic acid blocks breakdown of fats, it causes a decrease in free fatty acids in the blood and, as a consequence, decreased secretion of VLDL and cholesterol by the liver.
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