Club drug is an ambiguous and flexible term which applies to a diverse array of drugs. However, these drugs are often taken in combination or with other intoxicants. like alcohol, which is also a depressant. Many scientific publications have proven that such combinations are likely to affect the body and brain in ways that are more deleterious than either drug alone. So, combinatorial administration can certainly change the pharmacological effects of such drugs & make them more lethal.
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